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Lead Software Engineer (Back-End Engineer)

Actively Reviewing the Applications

OpenEye, Cadence Molecular Sciences

India, Karnataka, Bengaluru Full-Time
Posted 1 day ago Apply by May 3, 2026

Job Description

Over the last eight years, OpenEye Scientific has developed the field’s most advanced large-scale compute platform, Orion, built on Amazon Web Services. In this position, you will be working at the cutting edge of cloud computing, C++/Python development, and advanced MD simulation techniques. Your work will have the potential to make a major impact in drug discovery, and will be available to many pharmaceutical and biotech companies.

Job Summary: Scientists around the world use Orion for early-stage drug discovery and design in the pursuit of improving human health. Orion combines the power of advanced HPC, computational methods, and in-browser 3D visualization & modeling to solve problems in drug discovery & design. Our innovative solutions enable customers to routinely model billions of compounds in-silico. Orion enables our customers to interactively explore chemical space, evaluate designs and gain scientific understanding.

As a Back-End Engineer, you’ll work with designers, scientists, and software engineers to enhance & extend Orion's capabilities -- architecting and optimizing the high-performance compute and storage systems that drive groundbreaking scientific discoveries. You'll be part of a team building cutting edge features, as well as helping to modernize existing software.

Qualifications & Experience:

  • Bachelor’s degree in computer science/engineering, biology/chemistry or similar
  • 5+ years of experience designing, developing, troubleshooting and debugging complex distributed systems as part of a team
  • Expert in Python, pytest, packaging, and Django
  • Expert in GoLang, testing, packaging, and client/server, and familiarity with writing servers/clients
  • Experience with PostgreSQL, SQLite, and relational database optimization and structural design
  • Experience in Life Sciences, HPC, AWS, Docker, and containerized systems
  • Experience with unit & end-to-end testing, CI/CD, source control, code review, comfortable using command line interfaces
  • Strong background of computer science fundamentals (data structures, algorithms)
  • Passionate to learn and explore new technologies and demonstrates good analysis and problem-solving skills

Interpersonal skills required:

  • Ability to establish a close working relationship with peers in development, science, design and customer success, often across time zones
  • Take initiative to solve unexpected challenges during development
  • Willing to expand their knowledge and skills in both technical and scientific areas
  • Push to raise the bar while always operating with integrity

OpenEye, Cadence Molecular Sciences is passionate about science and about taking care of team members, with leaders supporting your development and recognizing your contributions by providing an unmatched total compensation package in a collaborative, caring, energetic and fun work environment.

We’re doing work that matters. Help us solve what others can’t.
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